asthma-and-allergy-:-a-story-of-fungi-in-the-nose

Asthma and allergy: a story of fungus in the nose

December 18, 2024

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Portuguese researchers analyzed the populations of fungi that line our nasal walls. They discovered that people with asthma or allergies have a much more diverse mycobiome than healthy individuals. These fungi could affect the immune system at the level of nasal tissues and be involved in both pathologies.

Illustration of inhaled pollen grains

Pollen is one of the environmental factors that can contribute to asthma attacks.

AFP – NEMES LASZLO/SCIENCE PHOTO LIBRA / NLA / Science Photo Library

The many research studies on the intestinal microbiota have raised it to the rank of celebrity. If you are looking to shine at the next Christmas Eve, you may need another lead, and why not: the nasal mycobiome. Behind this term hides the set of fungal species present on the walls of the nose. Its etymological origin comes from the ancient Greek mukes (mukes), "mushroom", and "biome" derived from the Greek bios (bios), which means "life". Many studies have analyzed the role of microbial populations in the development of allergic diseases, but little is known about nasal fungal populations and their potential association with allergic inflammatory diseases," deplores Luis Delgado, researcher at the University of Porto, during an interview for Science and Future. With his team, he highlighted the traces of different populations of fungi in people with asthma and allergic rhinitis. Their mycobiome is much more diverse than that of healthy individuals. The results of this work were published in the journal Frontiers in Microbiology.

Asthma and allergic rhinitis are often associated

Asthma Allergic rhinitis (hay fever)

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