Babies are born with high levels of Alzheimer's biomarkers, a scientific mystery

Babies born with high levels of Alzheimer's biomarkers, a scientific mystery

August 13, 2025

By Coralie Lemke THE Subscribers

They've barely been born, yet they already have high levels of p-tau217, a typical biomarker of Alzheimer's disease. What might this protein do in babies' brains, and how do they get rid of it?

baby

Newborns have Alzheimer's biomarkers three times higher than those of older adults with the disease.

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The discovery is disconcerting and counterintuitive, to say the least. Newborns have blood levels of a typical Alzheimer's biomarker, called p-tau27, three times higher than those of older adults with the disease, according to a study published in Brain Communications.

A few months later, these levels returned to normal. Faced with this rather enigmatic phenomenon, a team is working to understand what this biomarker might be used for early in life and how babies manage to get rid of it. The team hopes to find a new way to combat the development of Alzheimer's disease in adults.

Alzheimer's disease Tau protein

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