bacteria-attacking-tumors,-the-promises-of-new-cancer-vaccines

Bacteria attack tumors, promises of new cancer vaccines

October 30, 2024

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Two laboratories at Columbia University have developed a bacterial anti-cancer vaccine. Currently being tested on mice, the vaccine is composed of bacteria programmed to generate an effective immune response. A new technique that opens the way to customizable vaccines. Explanations with Mathieu Rouanne, a French researcher and co-author of the study.

Once the bacteria are injected into the body, they will go around the tumor cells and proliferate there.

Nam Y. Huh/AP/SIPA

"We could develop a vaccine personalized for each patient and adapted to all types of tumors, whether they are advanced or not", reveals Mathieu Rouanne, a surgeon by training, now an associate researcher at Columbia University (United States).

The ambition of the French researcher is motivated by a study published in Nature, in which he participated. Teams from the bioengineering laboratory, which includes Andrew Redenti, the study's first author, and the Department of Microbiology and Immunology at Columbia University, have developed a prototype bacterial vaccine capable of attacking cancer cells without affecting healthy cells.

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