a-collagen-heart-valve-could-improve-the-care-of-“blue-children”

A collagen heart valve could improve the care of “blue children”

July 24, 2024

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The development by an Inserm team of a collagen heart valve that is more stable than other available materials offers hope for improved surgical management of a congenital disease, tetralogy of Fallot, also known as "blue baby disease". These promising results found in animal trials must now be confirmed before moving on to clinical trials.

pulmonary valve

MRI image showing the reconstructed pulmonary valve (circled in red) closing perfectly after 7 days of implantation.

Fabien Kawecki/Inserm

New treatment path for Tetralogy of Fallot, a congenital pediatric heart disease that affects one in 4,000 births, and is also called "blue baby disease." It all relies on a new, entirely biological valve created from human collagen with no risk of rejection, unlike the materials used to date.

This work was carried out in collaboration with the Massachusetts Institute of Technology, the famous MIT, and has just been published in the journal Science Translational Medicine. .The team of Fabien Kawecki (University of Bordeaux, Inserm), who has been working on the subject for several years, is proposing a new approach here.

Cardiology Biomaterial Collagen

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