Facing antibiotic resistance, the feat of a virus created from scratch

In the face of antibiotic resistance, the feat of a virus created from scratch

February 28, 2026

By Nicolas Gutierrez C. THE Subscribers

A new method facilitates the production of synthetic bacteriophages, a new weapon against antibiotic resistance.

These bacteriophages can be designed to target different bacteria and produce a variety of molecular tools.

These bacteriophages can be designed to target different bacteria and produce a variety of molecular tools.

Photo by SKU / SCIENCE PHOTO LIBRARY VIA AFP

Synthesizing a living being from scratch, that is the ambition of the synthetic biologyA scientific field that is advancing rapidly and already showing concrete results. This is particularly true of viruses, the simplest organisms (to the point that there is still no consensus on their status as living beings), and therefore the easiest to produce. The most recent example was presented on January 23, 2026, in the journal PNAS, by researchers from New England Biolabs and Yale University, in the United States, using an innovative method.

This bacteriophage would strengthen our arsenal against... antibiotic-resistant bacteriaTo better understand their method and the potential uses of this synthetic virus, Science and Future discussed with the two study directors, biochemist Greg Lohman of New England Biolabs and virologist Paul Turner of Yale University.

Virus Bacterium Antibiotic resistance Synthetic biology Antibiotics

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