the-great-discoveries-:-glp-1,-the-all-purpose-hormone

The Big Discoveries: GLP-1, the All-Purpose Hormone

August 18, 2025

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By Coralie Lemke THE Subscribers

Indicated in the treatment of diabetes and then obesity, drugs imitating this hormone show promising therapeutic effects in cardiovascular and neurodegenerative diseases, addictions, etc.

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Ozempic

Medicines GLP-1 analogues (here an injection of Ozempic) have the effect of increased insulin secretion and a reduction in blood sugar.

NATALIA VARLEI/ ALAMY / PHOTO12

This article is taken from the monthly Sciences et Avenir n°941-942, dated July-August 2025.

It had the effect of a cannonball in the world of research and was qualified in 2023 as "breakthrough of the year" » by the magazine ScienceProduced in the intestine after a meal, the incretin hormone GLP-1 stimulates insulin secretion from the pancreas. This key role in regulating blood sugar is accompanied by a slowing of gastric emptying, which prolongs the feeling of satiety.

GLP-1 Obesity Type 2 diabetes

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