The French Monitoring Centre for Drugs and Drug Addiction (OFDT) is warning about the emergence of " 40 new psychoactive substances (NPS) identified between 2024 and 2025, including 26 in 2025", in the biannual report of its National System for the Identification of Toxic Substances (SINTES) published Thursday, June 11, 2026.
Warning about a diversification of cannabis forms
The OFDT adds that This increase is driven by the diversification of semi-synthetic cannabinoids."SINTES collects samples in order to..." to identify changes in the composition of drugs, particularly when their use has caused unusual and undesirable effects“.
The document reveals that The number of these collections increased by 31% in one year, rising from 742 in 2024 to 1,086 in 2025, after a total of 732 collections carried out in 2023", particularly due to a " increasing diversification of substances circulating in the territory"The observatory observes" diversification " of the forms of cannabis including " an increase in edible products", and adds that " Synthetic cannabinoids are present in many collected e-liquids, as well as being used as an adulterant in products sold under the name CBD."In 2025, the increase in the number of cannabis collections will be accompanied, according to the OFDT (French Monitoring Centre for Drugs and Drug Addiction)..." a significant number of health reports: 41 for unexpected effects, 45 for adverse effects, including 21 serious ones“.
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Cocaine, heroin, cathinones
The report also points to concentrations " increasingly higher » for the cocaine, which indicates " an ever-increasing availability of products with high levels and minimal adulteration“. Regarding heroin, " Collections during the 2024-2025 period did not reveal a significant disruption in its availability." , the OFDT states in a press release published with the report. The latter also notes a heterogeneity of content (…) for the brown form of heroin“.
For the synthetic cathinonesincluding 3-MMC, the OFDT notes in its press release a very dynamic market, heavily influenced by regulatory changes and international supply chains", as well as the emergence " constant new substances and substitution phenomena“Several cathinones are subject to intensive monitoring by the early warning system European.
Established in 1999 by the OFDT, SINTES is a tool for monitoring the toxicology of illicit drugs. Through this system, the OFDT manages a network " composed of 19 local coordinating bodies, including five in the overseas territories“.
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