Even at a lethal dose, all influenza viruses appear vulnerable to the same combination of three antibodies developed by a U.S. team. Administered preventively the day before or up to five days after lethal infection, the treatment protected up to 100% of the mice studied and did not lead to any development of resistance in the viruses, according to this new work published in the journal Science Advances.
By Camille Gaubert THE Subscribers
Against the flu, the most effective approach may not be to target the viruses, but the infected cells! Administered preventively or up to 5 days after a lethal infection, a combination of antibodies targeting infected host cells allows the survival of 50 to 100 TP3T mice, including against H1N1 and H7N9 flu, a new study shows.
Every year, the flu kills an average of 9,000 people in France and 500,000 worldwide.
Photo by KATERYNA KON/SCIENCE PHOTO LIBRA / KKO / Science Photo Library via AFP