up to one in three adults is affected by the MALD

Up to one in three adults is affected by MASLD

July 3, 2026

By Laetitia Maouchi THE Subscribers

By walking 350 kilometers, doctoral student Sonny Yde aims to raise awareness of MASLD, a liver disease that is progressing in conjunction with the rise in metabolic disorders and obesity. This initiative stems from a desire to remind people that regular physical activity remains one of the best forms of prevention.

Metabolic liver diseases affect one in three people.

Metabolic liver diseases affect one in three people.

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He is a doctoral student on foot, and he is already halfway between Paris and Deauville. He is walking with a specific goal: to cover these 350 kilometers to talk about a group of liver diseases, known as MASLD. “These diseases are progressing at an alarming rate, but they remain largely unknown to the general public.”, notes Sonny Yde, a doctoral student in molecular biology, specializing in metabolic liver diseases at Sorbonne University.

Long known as "non-alcoholic fatty liver disease", MASLD – for Metabolic Dysfunction-Associated Steatotic Liver Disease – is an accumulation of fat in the liver linked to metabolic disorders. "Initially, it is simply an accumulation of fat without any immediate pathological consequences.", explains to Science and Future François Pattou, surgeon at the University Hospital of Lille and director of a research team on metabolic diseases at Inserm. But this silent phase can evolve into a more serious form. This is when inflammation appears and the disease becomes risky, with complications such as fibrosis, cirrhosis, or liver cancer.

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